On October 5, after a final visit to Susy's grave, the Clemens family moved from Elmira to New York City, where it spent the last weeks before departing at the Grosvenor Hotel.... And on the evening of the twenty-third the family boarded the Princess Irene in high hopes of Olivia's recovery and their continued financial tranquility.
From Gribben's Mark Twain's Literary Resources, Vol 2: “The Old Men” (poem, published in 1902): On 12 October 1903 Clemens thanked Frank N. Doubleday for some books, adding, “I have been reading “The Bell Buoy & “The Old Men’ over & over again. . . . “The Old Men,’ delicious, isn't it? And so comically true. I haven't arrived there yet, [but] suppose I am on the way’ (MTL, p. 746; ALS in MTP), When we are aged men, Kipling wrote, “We shall peck out and discuss and dissect, and evert and extrude to our mind,/The flaccid tissues of long-dead issues offensive to God and mankind—/. . . . And whatever we do, we shall fold our hands and suck our gums and think well of it,”
[Villa Reale di Quarto] Olivia’s doctors having advised a milder climate, Clemens removed his family to this Tuscan villa in the autumn of 1903. The family party consisted of Samuel, Olivia, Clara, and Jean, together with Katy Leary, their longtime servant, and Margaret Sherry, a trained nurse. They left New York in the steamer Princess Irene on 24 October, arriving at Genoa on 6 November. They made their way by train to Florence and were installed in the Villa di Quarto by 9 November. Later that month they were joined by Isabel V. Lyon, who had been hired in 1902 as Olivia’s secretary, but had since assumed more general duties; Lyon’s mother accompanied her.
"[Villa di Quarto]," in Autobiography of Mark Twain, Volume 1. 2010