August 21 Thursday – The Clemens party arrived in Liverpool. An hour later, Sam wrote from the Washington Hotel to Dr. John Brown, a letter of apologies for not being able to make the trip to Edinburgh to see him.

“It is a great disappointment, for we wanted to show you how much ‘Megalopis’ has grown, (she is 7 now) & what a fine creature her sister (aged 5) is, & how prettily they both speak German. There are six persons in my party, & they are as difficult to cart around as nearly any other menagerie would be” [MTLE 4: 86].

August 18 Monday – “Left London at 10.30 AM for Windermere—changed cars all day. Too much variety” [MTNJ 2: 339].

August 19 Tuesday – From Sam’s notebook:

Went up Windermere Lake in the steamer.—Talked with the great Darwin [MTNJ 2: 339]. Note: Charles Robert Darwin (1809-1882). Windermere is over 80 miles north of Liverpool; Condover some 70 miles south of Liverpool.

August 3 Sunday – The Clemens family ended their visit at Condover Hall and went to Oxford, arriving at about 6 PM. There they sent the children on to Brunswick House Hotel, London with Rosa and were shown the colleges by Edward Wyndham [MTNJ 2: 337&n93].

July 28 Monday – The Clemens family traveled just over 70 miles to spend a week in Condover Hall, in North Shropshire on the west English coast. Paine: “For more than two years they had had an invitation from Reginald Cholmondeley to pay him another visit” [MTB 646]. From Sam’s notebook:

July 20 Sunday – The Clemens family arrived in London in the morning. Sam wrote in his notebook that the family arrived in London at 8 AM; that it was rainy and cold. They stayed at the Brunswick House Hotel, Hanover Square.

July 26 Saturday – Sam met Lewis Carroll, who later wrote in his diary, “Met Mr. Clemens (Mark Twain), with whom I was pleased and interested” [Green 382].

NOVEMBER 11 MONDAY – THE CLEMENS FAMILY LEFT ROME AT 10:50 AM, AND RETURNED TO FLORENCE, ITALY AT 6:50 PM, WHERE THEY SPENT THE NIGHT AT THE HOTEL DE NEW YORK.
THEY WERE HEADED NORTH TO SPEND THE WINTER IN MUNICH, A 600 MILE TRIP WITH 36 HOURS ON SLOW TRAINS, AND FOUR OVERNIGHT HOTEL STOPS TO MAKE THE JOURNEY MORE BEARABLE FOR LIVY.
SAM’S NOTEBOOK:

From page 269 The Life of Mark Twain - The Middle Years 1871-1891:

October 28 Monday – The Clemens family left Florence for Rome. The trip took 8 hours and they arrived at 4:30 PM [MTNJ 2: 235]. The party stayed at the Hotel d’Allemania. Sam noted the cost of the rooms, three coffees, one beefsteak and three “table d’hotes” (communal table, full-course meal) totaling 48.25 francs, paid at 5 PM.

There does not seem to be any information of what route they took.

Bædeker Central Italy and Rome (1869) 

October 21 Monday – Livy wrote from Florence to her mother:
Florence is much more restful than Venice, because we have no social demands—and one ought to know no one when they are visiting picture galleries—The Chamberlains are a perfect delight, they never tax us in the least they are helpful to us and are bright beyond expression.
Mr. & Mrs. Augustus P. Chamberlaine were friends of Ralph Waldo Emerson. The Clemens met them in Venice.

October 17, 1878: In Venice, the Clemens family had increasingly been pressed by visitors who discovered Mark Twain was in the city. After three weeks of this, they left Venice for Florence, a ten hour train ride. They stayed at the Hotel de New York.

From page 269 The Life of Mark Twain - The Middle Years 1871-1891: