January 29 Tuesday – Yellow fever still raged in Hannibal. Sam’s sister Pamela wrote Orion in St. Louis:

“I suppose you have not been attacked with the yellow fever, that by the way is raging so her that it is feared it will carry off nearly half the inhabitants, if it does [not] indeed depopulate the town. In consequence of it many of our best citizens intend starting for California so soon as they can make preparations” [Wecter 214].