From 1849 to 1868, then sold to the Columbus, Springfield and Cincinnati.  In 1869, leased to Cincinnati, Sanduisky and Cleveland Railroad Company.  

November 1, 1890, all the titles were leased to the Cleveland, Cincinnati, Chicago and St. Louis Railway Company, and now operated by that Company.

There is a problem with the USGS map of Dayton, Ohio but these two railroads either share a track or run very close to each other.  Also, the plotted route through Greene County is not found on the map but the route continues on the Springfield quad.  Both quads are from 1904.