The Cleveland and Pittsburgh Railroad was chartered in 1836, due to public support in building a railroad line between Cleveland and Pittsburgh. Construction of the line was completed in 1852, with additional branch lines to Akron, Ohio, and Wheeling, West Virginia. In 1871, the C&P was leased to the Pennsylvania Railroad for a 999 year lease, thus, giving the PRR access to Cleveland.
An anecdote found in Day By Day for March 4, 1906:
Mark Twain Got the Stateroom.
The Sunbury and Erie Railroad Company (also known as the Erie and Sunbury Railroad) was chartered by the Commonwealth of Pennsylvania in 1837, to build a rail line connecting towns between Sunbury and Erie, Pennsylvania.
The Philadelphia and Reading Railroad (P&R) was one of the first railroads in the United States. Along with the Little Schuylkill, a horse-drawn railroad in the Schuylkill River Valley, it formed the earliest components of what became the Reading Company.
The Central Railroad of New Jersey, also known as the New Jersey Central or Jersey Central Lines (reporting mark CNJ), was a Class I railroad with origins in the 1830s.
The Central Pacific Railroad (CPRR) was a rail company chartered by U.S. Congress in 1862 to build a railroad eastwards from Sacramento, California, to complete the western part of the "First Transcontinental Railroad" in North America.